Hyaluronic Acid (HA), also known as Hyaluronan, is an acidic mucopolysaccharide composed of D-glucuronic disaccharide unit and N-acetylglucosamine.
It can be found in intercellular, vitreous body and joint synovial fluid; also it is an important component of skin. Nowadays, HA is obtained by microbiological fermentation, and sold in the form of its sodium salt (Sodium Hyaluronate). There are many functional groups such as hydroxyl group and carboxyl group distributing in the outer layer of HA's molecular structure. These groups are able to hydrogen bonds with water molecules, which make HA be an extremely strong absorbent. So Hyaluronic Acid has a great moisturizing effect. molecular weight ≤0.6x106 DA.
As a natural moisturizer, Hyaluronic Acid is widely used in various cosmetics. It is also named the fourth generation of cosmetic additives or biomimetic cosmetic additives. More importantly, HA is the best cosmetic moisturizing ingredient known in the nature at present.
Chemically speaking, Sodium Hyaluronate is a form of sodium salt of Hyaluronic Acid. From a commercial perspective, Hyaluronic Acid we usually called is Sodium Hyaluronate. HA is a colloquial name. If a product contains Hyaluronic Acid, actually it contains Sodium Hyaluronate, the product has a hydrating effect. Hyaluronic Acid is also known as Hyaluronan. Therefore, if the product is commonly referred to as Hyaluronic Acid or Hyaluronan, its main ingredient is Sodium
Our Hyarolic Acid at deoorganic ,with a molecular weight of ≤0.6x106, quickly replenish moisture and nutrition for skin
Hyaluronic acid does help promote skin cell regeneration by offering extra hydration and barrier protection to the skin. This naturally leads to healthier cells and a more vibrant complexion., hyaluronic acid also helps reduce and prevent age spots and pigmentation issues. But, it cannot do it on it’s own. When looking to treat dark spots, a vitamin c and product should be paired with hyaluronic acid.
By promoting proper moisture balance in the skin, hyaluronic acid prevents the over-production of oil that clogs pores and causes breakouts.
HA is a polymer biological component with a straight chain structure. It has a strong water-holding capacity; and it is easy to form a dense water-soluble polymeric network structure in water. Therefore, its aqueous solution can maintain high viscosity and elasticity, and has a thickening effect. HA has good compatibility with emulsifiers and surfactants. When its aqueous solution mixes with oil phase cosmetics ingredients, the texture of cream, emulsion can be fine and uniform. And longterm storage will not be stratified and water-permeable. It indicates that HA can promote and stabilize emulsification.
Nourishing skin HA has the dual effects of moisturizing and nourishing skin, which is unmatched by other moisturizers. When apply on skin surface, macromolecular HA can rapidly form a permeable hydrated film on skin surface to soften the cuticle by hydration; thereby it increases the absorption and utilization of stratum corneum for the active substance. At the same time, HA becomes an effective medium for the delivery of active ingredients in cosmetics, due to skin's matrix structure. deoorganic Low-molecular-weight HA can directly penetrate into the dermis to dilate capillaries, increase blood microcirculation, and improve intermediate metabolism. HA acts as a trans-dermal delivery for other active or nutrient components in the skin. Thereby HA can improve the physiological condition of the skin; and it provides a superior external environment for the synthesis of dermal collagen and elastin. Thus HA enhances the supply of nutrients and then produces a nourishing skin function.
Antibacterial and anti-inflammation It has been reported that low molecular weight HA can inhibit the pathogens growth and pathological reactions of rodents. It has an antibacterial and anti-inflammatory effect. Due to the unique water absorption and moisturizing function of macromolecular HA, when applied to the skin surface, it is easy to form a hydrated film. The film effectively prevents the skin from bacteria and blocks bacteria from invading the skin. Indirectly, HA exerts antibacterial and anti-inflammatory effect. In addition, HA binds to proteins in the skin matrix. It exists as a protein complex in the intercellular space to form a gel. The gel can bind the cells together. Thereby HA protects cells from pathogenic bacteria and prevents infection.
Anti-aging Studies have found that when HA binds to the cell surface, it blocks the release of some enzymes; it reduces free radicals. HA can mainly restrict several enzymes close to the cell membrane. The enzymes produce free radicals and lipid peroxidation. Then it can reduce the inflow of hydroxyl radicals on the cell membrane surface; and it prevents the destruction of cell structure. Thus HA can exert its anti-wrinkles and anti-aging effects. After properly applying a certain amount of HA to the skin, HA can quickly bind to the cell surface. It can timely transmit the external growth signal to the cell, and then directly promote tissue's proliferation, reconstruction and repair. Also HA promotes the recovery of ECM function.
HOW TO DISSOLVE
TYPICAL concentration is at 0.1%-2% of HA (equals 1g of HA in 100 ML water)
(HA) does not readily dissolve in water as it binds water very quickly.
Thus, HA needs to be carefully sprinkled into the water under constant high-speed stirring (preferably with a hand mixer or vortex mixer). The mixture starts then thickening quickly and becomes a gel. At that point no additional HA can be added as there is no water left for HA to be dissolved in. Any additional HA would only form lump.
CERTIFICATE OF ANALYSIS
Molecular weight ≤99 Dalton (LMW)
Appearance White powder
Glucuronic acid ≥44%
Transparency （0.1%solution） ≥99.0%
Ash content ≤13.0%
Heavy metals ≤10ppm
Total Plate count ≤100cfu/g
Yeast & mold ≤100cfu/g
Escherichia coli Negative
EXPIRY DATE: APRIL 2026
At Deo Organic we have developed a sophisticated software program that calculates the shipping costs on your order. Actual shipping charges are derived using a Konga, GIG, Sendbox, Fed-Ex, DHL shipping matrix that factors actual weight, or dimensional weight (Length x Width x Height) depending upon which is greater. We then apply the heavily discounted volume rate that we contract annually with Konga, GIG, Sendbox, Fed-Ex, DHL. The savings are passed on directly to you, and we do not charge any additional handling fees. Charges can be seen on-line before you finalize your order. There are no surprises!